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Curbing the burden of lung cancer

null

《医学前沿(英文)》 2016年 第10卷 第2期   页码 228-232 doi: 10.1007/s11684-016-0447-x

摘要:

Lung cancer contributes substantially to the global burden of disease and healthcare costs. New screening modalities using low-dose computerized tomography are promising tools for early detection leading to curative surgery. However, the screening and follow-up diagnostic procedures of these techniques may be costly. Focusing on prevention is an important factor to reduce the burden of screening, treatment, and lung cancer deaths. The International Agency for Research on Cancer has identified several lung carcinogens, which we believe can be considered actionable when developing prevention strategies. To curb the societal burden of lung cancer, healthcare resources need to be focused on early detection and screening and on mitigating exposure(s) of a person to known lung carcinogens, such as active tobacco smoking, household air pollution (HAP), and outdoor air pollution. Evidence has also suggested that these known lung carcinogens may be associated with genetic predispositions, supporting the hypothesis that lung cancers attributed to differing exposures may have developed from unique underlying genetic mechanisms attributed to the exposure of interest. For instance, smoking-attributed lung cancer involves novel genetic markers of risk compared with HAP-attributed lung cancer. Therefore, genetic risk markers may be used in risk stratification to identify subpopulations that are at a higher risk for developing lung cancer attributed to a given exposure. Such targeted prevention strategies suggest that precision prevention strategies may be possible in the future; however, much work is needed to determine whether these strategies will be viable.

关键词: lung cancer     screening     risk factors     environmental    

Nanomaterials for environmental burden reduction, waste treatment, and nonpoint source pollution control

Guobin SHAN , Rajeshwar D. TYAGI , Rao Y. SURAMPALLI , Tian C. ZHANG

《环境科学与工程前沿(英文)》 2009年 第3卷 第3期   页码 249-264 doi: 10.1007/s11783-009-0029-0

摘要: Nanomaterials are applicable in the areas of reduction of environmental burden, reduction/treatment of industrial and agricultural wastes, and nonpoint source (NPS) pollution control. First, environmental burden reduction involves green process and engineering, emissions control, desulfurization/denitrification of nonrenewable energy sources, and improvement of agriculture and food systems. Second, reduction/treatment of industrial and agricultural wastes involves converting wastes into products, groundwater remediation, adsorption, delaying photocatalysis, and nanomembranes. Third, NPS pollution control involves controlling water pollution. Nanomaterials alter physical properties on a nanoscale due to their high specific surface area to volume ratio. They are used as catalysts, adsorbents, membranes, and additives to increase activity and capability due to their high specific surface areas and nano-sized effects. Thus, nanomaterials are more effective at treating environmental wastes because they reduce the amount of material needed.

关键词: nanomaterials     industrial     agricultural     nonpoint source pollution     environmental burden reduction    

Identification and assessment of environmental burdens of Chinese copper production from a life cycle

Xiaolong SONG,Jianxin YANG,Bin LU,Bo LI,Guangyuan ZENG

《环境科学与工程前沿(英文)》 2014年 第8卷 第4期   页码 580-588 doi: 10.1007/s11783-013-0599-8

摘要: The environmental burdens of Chinese copper production have been identified and quantified in the context of typical technologies, materials supplies and environmental emissions by a life cycle approach. Primary and secondary copper production using copper ores and scraps, respectively, were analyzed in detail. The flash and bath smelting approaches and the recycling of copper scraps were selected as representative copper production processes. A quantitative analysis was also conducted to assess the influence of material transport distance in copper production. Life cycle assessment (LCA) results showed that resources depletion and human health contribute significantly to environmental burdens in Chinese copper production. In addition, the secondary copper production has dramatically lower environmental burdens than the primary production. There is no obvious distinction in overall environmental burdens in primary copper production by flash or bath smelting approach. However, resources depletion is lower and the damage to human health is higher for flash smelting approach. Ecosystem quality damage is slight for both approaches. Environmental burdens from the mining stage contribute most in all life cycle stages in primary copper production. In secondary copper production, the electrolytic refining stage dominates. Based on the life cycle assessment results, some suggestions for improving environmental performance were proposed to meet the sustainable development of Chinese copper industry.

关键词: copper production     environmental burden     life cycle assessment     refined copper    

The epidemiology of norovirus gastroenteritis in China: disease burden and distribution of genotypes

Honglu Zhou, Songmei Wang, Lorenz von Seidlein, Xuanyi Wang

《医学前沿(英文)》 2020年 第14卷 第1期   页码 1-7 doi: 10.1007/s11684-019-0733-5

摘要: With the improvements of sanitation and nationwide safe water supply the occurrence of bacterial diarrhea declined remarkably, while viruses became the leading causes of acute gastroenteritis (AGE). Of these viruses, noroviruses (NoVs) are responsible for a considerable burden of gastroenteritis, especially in children<2 years and elderly≥65 years. NoVs circulating in the Chinese population are antigenically highly diverse with the genotype GII.4 being the dominant strain followed by GII.3. Given the widespread contamination in environmental sources, and highly infectious nature of NoVs, vaccination would be the desirable strategy for the control of NoV infections. However, a better understanding of acquired immunity after infection, and a reliable immunological surrogate marker are urgently needed, since two vaccine candidates based on virus-like particles (VLPs) are currently moving into clinical evaluations in China.

关键词: molecular epidemiology     norovirus     disease burden     genotype     China    

先进设备减轻糖尿病患者的葡萄糖监测负担

Chris Palmer

《工程(英文)》 2021年 第7卷 第5期   页码 547-549 doi: 10.1016/j.eng.2021.03.008

An overview of the environmental finance policies in China: retrofitting an integrated mechanism forenvironmental management

LI Wei,HU Mengze

《环境科学与工程前沿(英文)》 2014年 第8卷 第3期   页码 316-328 doi: 10.1007/s11783-014-0625-5

摘要: Considering the significant roles of the policies in developing environmental finance, an overview is conducted on the environmental finance policies (EFPs) in China. This paper analyzed the definition, scope, evolution and main instruments of EFPs. The implementation progress of financial activities on each instrument are investigated respectively. Then the experiences learned from and failures discovered in the development of the EFPs are discussed well recommendations for further improvement of the EFPs and their implementation are provided. Our study found that the EFPs have been established in China after a four-phase evolution since the early 1980s. The policies have played a critical role in leading to a rapid development in environmental finance by involving more financial instruments to accomplish the objective-led environmental plans. Driven by the policies, the new green credit (GC), green security (GS), and green insurance (GI) instruments have been phased in as supplements to the conventional command and control approaches to improve the environmental governance of financial activities and pollution sources. However, the market mechanism of financial institution is limited due to their defensive and incapable performance on implementation some of EFP instruments. To further strengthen the effectiveness of EFPs in facilitating environmental management, recommendations are made mainly on the aspects including developing more specific policy guidelines, enhancing information sharing and disclosure, providing sufficient economic incentives, establishing environmental liabilities with financial activities, and involving issues related to climate change, and biodiversity and ecosystem service.

关键词: environmental finance policy     integrated mechanism     phased evolution     implementation progress     financial institution     environmental management    

Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy

Min Zhang, Jingwen Yang, Wenjing Hua, Zhong Li, Zenghui Xu, Qijun Qian

《医学前沿(英文)》 2019年 第13卷 第1期   页码 32-44 doi: 10.1007/s11684-018-0678-0

摘要:

Immunotherapy has become the fourth cancer therapy after surgery, chemotherapy, and radiotherapy. In particular, immune checkpoint inhibitors are proved to be unprecedentedly in increasing the overall survival rates of patients with refractory cancers, such as advanced melanoma, non-small cell lung cancer, and renal cell carcinoma. However, inhibitor therapies are only effective in a small proportion of patients with problems, such as side effects and high costs. Therefore, doctors urgently need reliable predictive biomarkers for checkpoint inhibitor therapies to choose the optimal therapies. Here, we review the biomarkers that can serve as potential predictors of the outcomes of immune checkpoint inhibitor treatment, including tumor-specific profiles and tumor microenvironment evaluation and other factors.

关键词: immune checkpoint     companion diagnosis     PD-L1     tumor mutation burden     immune score    

Trends of environmental accidents and impact factors in China

Pengli XUE, Weihua ZENG

《环境科学与工程前沿(英文)》 2011年 第5卷 第2期   页码 266-276 doi: 10.1007/s11783-010-0267-1

摘要: An overview of the spatial and temporal variations of the environmental accidents in China in recent years was presented in this paper using available data. The results showed that the frequency of pollution accidents was significantly decreased, from 3462 in 1990 to 462 in 2007. The water and air pollution accidents were found to be the dominant types, accounting for more than 80% of the total accidents. Considering the classification of environmental accidents at 4 scales, the general environmental accident, i.e., the least serious type, was the most frequent event, taking up 58.98% of the total pollution accidents. In addition, the distribution of environmental accidents was generally in accordance with the industrial layout in the country during the past decade. It is very important to note that the extraordinarily severe environmental accidents showed an increasing trend in underdeveloped regions, which was caused by the transfer and the development of heavy polluted industry in these areas. As to the losses of environmental accidents, the casualties presented an obvious reduction tendency, while the direct economic loss per accident tended to climb up. Furthermore, some key factors that affect the spatial and temporal tendencies of environmental accidents in China were discussed and some suggestions were put forward, hoping to shed light on environmental risk management and emergency plans making associated with environmental accidents in China.

关键词: environmental accidents     spatial and temporal trends     environmental risk    

Why does environmental compliance cost more than penalty?—A legal analysis on environmental acts of enterprises in China

DONG Hongwei

《环境科学与工程前沿(英文)》 2007年 第1卷 第4期   页码 434-442 doi: 10.1007/s11783-007-0069-2

摘要: In the environmental protection field of China, due to lower law-breaking cost but higher law-abiding cost , it is a common case that the enterprise chooses to break through the law on purpose. The punishment to the unlawful pr

关键词: law-abiding     punishment     environmental protection     law-breaking     enterprise    

Analysis of the current situation of environmental policy of China and establishment of distributed environmental

Chaoyang FU,Wangfeng LI

《环境科学与工程前沿(英文)》 2015年 第9卷 第2期   页码 310-316 doi: 10.1007/s11783-014-0658-9

摘要: In this study, China’s current macro-environmental policies as well as their implementation and management tools are analyzed. By using the basic economic methodology, detailed studies are conducted focusing on the implementation effect of contemporary China’s typical environmental policy of the total pollutant discharge quantity control type, and also the two types of environmental management tools are compared from the perspective of implementation costs and policy uncertainty. By introduction of distributed management tools into the implementation of environmental policies, market-oriented means and the methods of economic analysis are introduced into environmental policy decision-making mechanisms, which could afford a new method for changing the current relatively low efficiency of environmental policy, solving the problem of “government failure” in environmental policy implementation, and providing a new way to make environmental policy system more flexible and more efficient. It is of great practical significance to solve China's current structural, complex and accumulative environmental problems.

关键词: environmental policy     distributed environment policy     distributed parameter model     lumped parameter model    

Reducing environmental impacts through socioeconomic transitions: critical review and prospects

《环境科学与工程前沿(英文)》 2023年 第17卷 第2期 doi: 10.1007/s11783-023-1624-1

摘要:

● Reducing environmental impacts through socioeconomic structural transitions.

关键词: Environmental pressures     Environmental impacts     Nexus     Supply chains     Trade     Coupled systems    

Hydrogel photocatalysts for efficient energy conversion and environmental treatment

《能源前沿(英文)》 2021年 第15卷 第3期   页码 577-595 doi: 10.1007/s11708-021-0756-x

摘要: Photocatalysts have attracted great research interest owing to their excellent properties and potential for simultaneously addressing challenges related to energy needs and environmental pollution. Photocatalytic particles need to be in contact with their respective media to exhibit efficient photocatalytic performances. However, it is difficult to separate nanometer-sized photocatalytic materials from reaction media later, which may lead to secondary pollution and a poor recycling performance. Hydrogel photocatalysts with a three-dimensional (3D) network structures are promising support materials for photocatalysts based on features such as high specific surface areas and adsorption capacities and good environmental compatibility. In this review, hydrogel photocatalysts are classified into two different categories depending on their elemental composition and recent progresses in the methods for preparing hydrogel photocatalysts are summarized. Moreover, current applications of hydrogel photocatalysts in energy conversion and environmental remediation are reviewed. Furthermore, a comprehensive outlook and highlight future challenges in the development of hydrogel photocatalysts are presented.

关键词: hydrogel     photocatalysts     energy conversion     environmental treatment    

NewIndustrial Revolution and Environmental Protection

Qian Yi

《工程管理前沿(英文)》 2014年 第1卷 第1期   页码 71-75 doi: 10.15302/J-FEM-2014011

摘要: Serious environmental problems have appeared in China since the rapid economic growth 30 years ago, which affect human's health and become a limiting factor for further development. It has brought about the rethinking of traditional ways for economy development and environmental protection, and realized that the change in the model of development and environment protection is of significance. A new industrial revolution is needed for protecting the environment and promoting sustainable development. This paper discusses the characteristics of the new industrial revolution for sustainable development including cleaner production, circular economy, and industrial ecology. Lessons from China and abroad will be introduced to prove that new strategies for environment protection and economic development are needed.

关键词: industrial ecology     new industrial revolution     environmental protection     cleaner production     circular economy    

Addressing the environmental risk of persistent organic pollutants in China

Bin WANG, Jun HUANG, Shubo DENG, Xiaoling YANG, Gang YU

《环境科学与工程前沿(英文)》 2012年 第6卷 第1期   页码 2-16 doi: 10.1007/s11783-011-0370-y

摘要: The Stockholm Convention on persistent organic pollutants (POPs) was adopted in 2001. This year is the 10th anniversary of the adoption of the Convention. Until now, 22 chemicals or chemical categories have been listed as POPs in the Stockholm Convention. The POPs Research Center was established in Tsinghua University in the same year when the Convention was adopted. In the last ten years, much work has been done by Chinese researchers to understand the environmental risk of POPs in China. This article aims to review the recent research progress of our POPs Research Center and some other Chinese researchers’ studies in addressing the environmental risk of POPs, including the priority screening and inventory study of POPs, monitoring and modeling of POPs pollution and exposure, and environmental risk assessment and modeling of POPs. Although great advances in addressing the environmental risk of POPs have been made in recent years, we are still facing quite a few problems, such as data scarcity and uncertainty in environmental risk assessment of POPs. The study on the effect of POPs mixtures is in its infancy and currently POPs are usually assessed from legal perspective by risk assessment of single chemicals. These problems should be well addressed by further efforts. Further studies should also be taken in future to study environment risk of POPs by considering aspects of coupled dynamics between climate processes and POPs. Such sound scientific, risk-based information can support decision-making aiming to effectively minimize the risk level of POPs.

关键词: persistent organic pollutant (POPs)     environmental risk assessment     inventory     environmental monitoring     fugacity model     emerging POPs    

Insight of chemical environmental risk and its management from the vinyl chloride accident

《环境科学与工程前沿(英文)》 2023年 第17卷 第4期 doi: 10.1007/s11783-023-1652-x

摘要: The combustion of vinyl chloride (VC) after the train derailment accident in Ohio, USA in February, 2023 has caused widespread concern around the world. This paper tried to analyze several issues concerning the accident, including the appropriateness of the VC combustion in the emergency response in this accident, the meanings of so-called “controlled combustion”, the potential environmental risks caused by VC and combustion by-products, and follow-up work. In our view, this accident had surely caused environmental and health risks to some extent. Hence, a comprehensive environmental risk assessment is necessary, and then the site with risk should be comprehensively remediated, hazardous waste should be harmlessly treated as soon as possible. Finally, this accident suggests that further efforts should be taken to bridge the gap between chemical safety management and their environmental risk management.

关键词: Vinyl chloride     Combustion     Chemical safety management     Environmental risk     Emerging contaminants    

标题 作者 时间 类型 操作

Curbing the burden of lung cancer

null

期刊论文

Nanomaterials for environmental burden reduction, waste treatment, and nonpoint source pollution control

Guobin SHAN , Rajeshwar D. TYAGI , Rao Y. SURAMPALLI , Tian C. ZHANG

期刊论文

Identification and assessment of environmental burdens of Chinese copper production from a life cycle

Xiaolong SONG,Jianxin YANG,Bin LU,Bo LI,Guangyuan ZENG

期刊论文

The epidemiology of norovirus gastroenteritis in China: disease burden and distribution of genotypes

Honglu Zhou, Songmei Wang, Lorenz von Seidlein, Xuanyi Wang

期刊论文

先进设备减轻糖尿病患者的葡萄糖监测负担

Chris Palmer

期刊论文

An overview of the environmental finance policies in China: retrofitting an integrated mechanism forenvironmental management

LI Wei,HU Mengze

期刊论文

Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy

Min Zhang, Jingwen Yang, Wenjing Hua, Zhong Li, Zenghui Xu, Qijun Qian

期刊论文

Trends of environmental accidents and impact factors in China

Pengli XUE, Weihua ZENG

期刊论文

Why does environmental compliance cost more than penalty?—A legal analysis on environmental acts of enterprises in China

DONG Hongwei

期刊论文

Analysis of the current situation of environmental policy of China and establishment of distributed environmental

Chaoyang FU,Wangfeng LI

期刊论文

Reducing environmental impacts through socioeconomic transitions: critical review and prospects

期刊论文

Hydrogel photocatalysts for efficient energy conversion and environmental treatment

期刊论文

NewIndustrial Revolution and Environmental Protection

Qian Yi

期刊论文

Addressing the environmental risk of persistent organic pollutants in China

Bin WANG, Jun HUANG, Shubo DENG, Xiaoling YANG, Gang YU

期刊论文

Insight of chemical environmental risk and its management from the vinyl chloride accident

期刊论文